식물 바이러스 증식에 관여하는 기주 요인의 중요성 |
박미리, 김국형 |
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The Importance of Host Factors for the Replication of Plant RNA Viruses |
Mi Ri Park, Kook Hyung Kim |
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Abstract |
All viruses have few genes relative to their hosts. Viruses, thus, utilize many host factors for efficient viral replication in host cell. Virus-host interactions are crucial determinations of host range, replication, and pathology. Host factors participate in most steps of positive-strand RNA virus infection, including entry, viral gene expression, virion assembly, and release. Recent data show that host factors play important roles in assembling the viral RNA replication complex, selecting and recruiting viral RNA replication templates, activating the viral complex for RNA synthesis, and the other steps. These virus-host interactions may contribute to the host specificity and/or pathology. Positive-strand RNA viruses encompass over two-thirds of all virus genera and include numerous pathogens. This review focuses on the importance of host factors involved in positive-strand plant RNA virus genome replication. |
Key Words:
Host factor, Positive-strand RNA virus, Virus replication |
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