당귀로부터 분리한 decursinol angelate의 밀 붉은녹병에 대한 항균활성 |
윤미영, 김영섭, 최경자, 장경수, 최용호, 차병진, 김진철 |
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Antifungal Activity of Decursinol Angelate Isolated from Angelica gigas Roots Against Puccinia recondita |
Mi Young Yoon, Young Sup Kim, Gyung Ja Choi, Kyoung Soo Jang, Yong Ho Choi, Byeong Jin Cha, Jin Cheol Kim |
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Abstract |
Rust causes significant losses in the yield and quality of various crops. The development of new effective and environmentally benign agents against the pathogen is of great interest. In the course of searching a natural antifungal compound from medicinal plants, we found that the methanol extract of Angelica gigas roots had a potent control efficacy against wheat leaf rust (WLR) caused by Puccinia recondita. The antifungal substance was isolated from the methanol extract by silica gel column chromatography, alumina column chromatography and C18 preparative HPLC. It was identified as decursinol angelate by EI-MS and 1H-NMR data. In in vivo test, decursinol angelate effectively suppressed the development of WLR and red pepper anthracnose (RPA) among the 6 plant diseases tested. In addition, the wettable powder-type formulation of ethyl acetate extract of A. gigas roots significantly suppressed the development of WLR. The crude extract containing decursinol angelate and the chemical appear to be a potential candidate for control of WLR. In addition, this is the first report on the in vivo antifungal activity of decursinol angelate against WLR as well as RPA. |
Key Words:
Angelica gigas, Decursinol angelate, Fungicidal activity, Wheat Leaf rust |
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